(6R-cis)-3-(acetoxymethyl)-7-amino-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- CAS: 54083-02-2
- Purity: 99%
- Reputable factory supply (6R-cis)-3-(acetoxymethyl)-7-amino-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 54083-02-2 in stock with high standard
Reputable factory supply (6R-cis)-3-(acetoxymethyl)-7-amino-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 54083-02-2 in stock with high standard
- Molecular Formula: C11H14 N2 O6 S
- Molecular Weight: 302.308
- Vapor Pressure: 5.33E-14mmHg at 25°C
- Boiling Point: 559.8°Cat760mmHg
- PKA: 2.62±0.50(Predicted)
- Flash Point: 292.3°C
- PSA： 144.46000
- Density: 1.57g/cm3
- LogP: -0.25710
(6R-cis)-3-(acetoxymethyl)-7-amino-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(Cas 54083-02-2) Usage
|
General Description |
The chemical compound (6R-cis)-3-(acetoxymethyl)-7-amino-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a cephalosporin antibiotic. It belongs to the class of beta-lactam antibiotics and is used to treat a variety of bacterial infections. (6R-cis)-3-(acetoxymethyl)-7-amino-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid works by inhibiting the synthesis of the bacterial cell wall, leading to the eventual destruction of the bacteria. It is commonly prescribed for respiratory, skin, and urinary tract infections. Additionally, its acetoxymethyl group allows for improved absorption and distribution in the body, enhancing its effectiveness in combating bacterial infections. |
InChI:InChI=1/C11H14N2O6S/c1-5(14)19-3-6-4-20-10-11(12,18-2)9(17)13(10)7(6)8(15)16/h10H,3-4,12H2,1-2H3,(H,15,16)
54083-02-2 Relevant articles
An antibacterial drug cefoxitin acid synthesis method (by machine translation)
-
Paragraph 0016; 0018; 0019; 0020, (2016/12/01)
The invention discloses an antibacterial...
The synthesis of 7α methoxy 7β amidocephalosporanic acids by methoxylation of 7β (p nitrobenzyloxycarboxamido) cephalosporanic acid
Lunn,Mason
, p. 1311 - 1313 (2007/10/09)
-
54083-02-2 Process route
-
-
67-56-1
methanol
-
-
957-68-6
7-Aminocephalosporanic acid
-
-
54083-02-2
(6R )-3-acetoxymethyl-7t -amino-7c -methoxy-8-oxo-(6r H )-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
| Conditions | Yield |
|---|---|
|
With
sodium hydrogencarbonate;
In
diethyl ether;
at 30 ℃;
for 1h;
Temperature;
Large scale;
Enzymatic reaction;
|
-
![(6<i>R</i>)-3-acetoxymethyl-7<i>t</i>-(4-nitro-benzyloxycarbonylamino)-8-oxo-(6<i>r</i><i>H</i>)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid](/upload/2026/4/51d9e413690d4fd3800f703cbd022c56_83086961-6c55-4ec3-929a-36fda4df5d64.png)
-
54055-49-1
(6R )-3-acetoxymethyl-7t -(4-nitro-benzyloxycarbonylamino)-8-oxo-(6r H )-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
-
-
54083-02-2
(6R )-3-acetoxymethyl-7t -amino-7c -methoxy-8-oxo-(6r H )-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
3
steps
1: tetrahydrofuran
2: (i) (methoxylation), (ii) H2
, Pd-C, MeOH, THF, (iii) SiO2
, CH2
Cl2
3: CF3
CO2
H
With
trifluoroacetic acid;
In
tetrahydrofuran;
|
54083-02-2 Upstream products
-
35565-04-9
(6R )-3-acetoxymethyl-7t -amino-7c -methoxy-8-oxo-(6r H )-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester
-
54055-49-1
(6R )-3-acetoxymethyl-7t -(4-nitro-benzyloxycarbonylamino)-8-oxo-(6r H )-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
-
54055-50-4
(6R )-3-acetoxymethyl-7t -(4-nitro-benzyloxycarbonylamino)-8-oxo-(6r H )-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester
-
1214622-93-1
7β-Aminocephalosporanic acid
Leave Your Message
Related Products
